NON-INVASIVE DIAGNOSTICS OF THE FETAL GENDER BY PREGNANT WOMAN BLOOD IN OBSTETRIX

Markelova Anastasiya Nikolaevna, Candidate of medical sciences, assistant, sub-department of obstetrics and gynecology №1, Samara State Medical University (89 Chapaevskaya street, Samara, Russia),
markelova-an@mail.ru
Tezikova Tat'yana Arkad'evna, Deputy chief physician for obstetrics and gynecology, Samara region clinical hospital named after M.I. Kalinin (159 Tashkentskaya street, Samara, Russia), markelova-an@mail.ru
Likhodedova Vera Aleksandrovna, Candidate of medical sciences, head of obstetric observation unit, Samara region clinical hospital named after M. I. Kalinin (159 Tashkentskaya street, Samara, Russia),
markelova-an@mail.ru
Melod'eva Elena Viktorovna, Obstetrician-gynecologist, Samara region clinical hospital named after M.I.Kalinin (159 Tashkentskaya street, Samara, Russia), markelova-an@mail.ru

618.293-07:616.15-07-097.34

Background. Previously the diagnosis of the fetal gender was troublesome and was possible after 20 weeks of pregnancy by amniocentesis or cordocentesis. It is dangerous for both a mother and a fetus. The discovery of the extracellular fetal DNA, circulating in the mother's blood, gave an opportunity to non-invasively diagnose the fetal gender. The authors studied the possibility of optimizing the observation of pregnant women, the risk of having children with the fetus-connected diseases, based on early non-invasive determination of the fetal gender.
Materials and methods. The scientific research was carried out with new diagnostic kits for identification of the SRY gene by Y chromosome in maternal blood "DNA-child's sex", produced by Gen-technologia Ltd. (Russia).
Results. Sensitivity and specificity of the test system were equal to 100 %. Based on it the authors suggest a new plan of monitoring pregnancy of women, families of which had cases of the fetus-connected diseases.
Conclusions. The authors proved the possible of using the Russian non-invasive fetal gender diagnosis system in early pregnancy. On this basis, the researchers suggest a new plan of monitoring pregnancy of women, families of which had cases of the fetus-connected diseases.

fetus gender, non-invasive diagnostics, fetus-connected disease.

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